Tham khảo Metadoxine

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  5. Yang, Yoon Mee; Kim, Hyun Eun; Ki, Sung Hwan; Kim, Sang Geon (2009). "Metadoxine, an ion-pair of pyridoxine and l-2-pyrrolidone-5-carboxylate, blocks adipocyte differentiation in association with inhibition of the PKA-CREB pathway". Archives of Biochemistry and Biophysics. 488 (2): 91–9. doi:10.1016/j.abb.2009.07.007. PMID 19607801.
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  7. Cacciatore, L; Antoniello, S; Nigro, C; Vatiero, V; Lingetti, M (1988). "Metadoxine Treatment of Fatty Liver Associated with Chronic Hepatitis". Clinical Trials Journal. 25 (3): 220–6.
  8. Shenoy, Kotacherry T.; Balakumaran, Leena K.; Mathew, Philip; Prasad, Mohan; Prabhakar, Boddu; Sood, Ajit; Singh, Shivaram P.; Rao, Nagaraj P.; Zargar, Shoukat A.; Bignamini, Angelo A. (2014). "Metadoxine Versus Placebo for the Treatment of Non-alcoholic Steatohepatitis: A Randomized Controlled Trial". Journal of Clinical and Experimental Hepatology. 4 (2): 94–100. doi:10.1016/j.jceh.2014.03.041. PMC 4116708. PMID 25755546.
  9. 1 2 "Metadoxine extended release (MDX) for adult ADHD". Alcobra Ltd. 2014. Truy cập 2014-05-07.
  10. "Metadoxine - Drugs.com". Drugs.com. 2014. Truy cập 2014-05-08.
  11. Subcommittee on Attention-Deficit/Hyperactivity Disorder.; Steering Committee on Quality Improvement Management.; Wolraich, M; Brown, L; Brown, R. T.; Dupaul, G; Earls, M; Feldman, H. M.; Ganiats, T. G.; Kaplanek, B; Meyer, B; Perrin, J; Pierce, K; Reiff, M; Stein, M. T.; Visser, S (2011). "ADHD: Clinical Practice Guideline for the Diagnosis, Evaluation, and Treatment of Attention-Deficit/Hyperactivity Disorder in Children and Adolescents". Pediatrics. 128 (5): 1007–22. doi:10.1542/peds.2011-2654. PMC 4500647. PMID 22003063.
  12. 1 2 Manor, Iris; Ben-Hayun, Rachel; Aharon-Peretz, Judith; Salomy, Dana; Weizman, Abraham; Daniely, Yaron; Megiddo, Dalia; Newcorn, Jeffrey H.; Biederman, Joseph; Adler, Lenard A. (2012). "A Randomized, Double-Blind, Placebo-Controlled, Multicenter Study Evaluating the Efficacy, Safety, and Tolerability of Extended-Release Metadoxine in Adults with Attention-Deficit/Hyperactivity Disorder". The Journal of Clinical Psychiatry. 73 (12): 1517–23. doi:10.4088/jcp.12m07767. PMID 23290324.
  13. 1 2 Manor, Iris; Rubin, Jonathan; Daniely, Yaron; Adler, Lenard A. (2015). "Attention Benefits after a Single Dose of Metadoxine Extended Release in Adults with Predominantly Inattentive ADHD". Postgraduate Medicine. 126 (5): 7–16. doi:10.3810/pgm.2014.09.2795. PMID 25295645.
  14. Weisler, Richard; Adler, Lenard A; Rubin, Jonathan; Daniely, Yaron; Manor, Iris (2014). A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study of Metadoxine Extended Release 1400 mg Compared with Placebo Once Daily in 300 Adults with Attention-Deficit/Hyperactivity Disorder (PDF). AACAP 61st meeting.
  15. “Alcobra ADHD Candidate MDX Fails Phase III Trial | GEN”
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  17. Garber, Kathryn B; Visootsak, Jeannie; Warren, Stephen T (2008). "Fragile X syndrome". European Journal of Human Genetics. 16 (6): 666–72. doi:10.1038/ejhg.2008.61. PMC 4369150. PMID 18398441.
  18. Hagerman, R. J.; Berry-Kravis, E.; Kaufmann, W. E.; Ono, M. Y.; Tartaglia, N.; Lachiewicz, A.; Kronk, R.; Delahunty, C.; Hessl, D.; Visootsak, J.; Picker, J.; Gane, L.; Tranfaglia, M. (2009). "Advances in the Treatment of Fragile X Syndrome". Pediatrics. 123 (1): 378–90. doi:10.1542/peds.2008-0317. PMC 2888470. PMID 19117905.
  19. Tranfaglia, Michael R. (2011). "The Psychiatric Presentation of Fragile X: Evolution of the Diagnosis and Treatment of the Psychiatric Comorbidities of Fragile X Syndrome". Developmental Neuroscience. 33 (5): 337–48. doi:10.1159/000329421. PMID 21893938.
  20. Schumann, J; Rubin, J; Daniely, Y; Snape, M; Cogram, P (2014). Metadoxine Effects in the Fmr1 Knockout Mouse: A Novel Pharmacologic Approach to Treating Fragile X Syndrome. Gordon Research Conference in Fragile X and Autism-related Disorders.
  21. Dölen, Gül; Osterweil, Emily; Rao, B.S. Shankaranarayana; Smith, Gordon B.; Auerbach, Benjamin D.; Chattarji, Sumantra; Bear, Mark F. (2007). "Correction of Fragile X Syndrome in Mice". Neuron. 56 (6): 955–62. doi:10.1016/j.neuron.2007.12.001. PMC 2199268. PMID 18093519.
  22. "Alcobra announces results from Phase 2 clinical trial of MDX for Fragile X Syndrome". Alcobra Ltd. 2015. Truy cập 2015-06-24.

Tài liệu tham khảo

WikiPedia: Metadoxine http://www.alcobra-pharma.com/products.cfm?product... http://www.alcobra-pharma.com/releasedetail.cfm?Re... http://www.chemspider.com/Chemical-Structure.10307... http://files.shareholder.com/downloads/AMDA-1SVKDP... //www.ncbi.nlm.nih.gov/pmc/articles/PMC2199268 //www.ncbi.nlm.nih.gov/pmc/articles/PMC2888470 //www.ncbi.nlm.nih.gov/pmc/articles/PMC4116708 //www.ncbi.nlm.nih.gov/pmc/articles/PMC4369150 //www.ncbi.nlm.nih.gov/pmc/articles/PMC4500647 //www.ncbi.nlm.nih.gov/pubmed/11921498